Abstract Recent trials have shown the efficacy of trastuzumab deruxtecan (T-DXd) in HER2-negative patients, but there is not yet a way to identify which patients will best respond, especially with the inability of current HER2 IHC and FISH assays to accurately determine HER2 expression in the unamplified setting.Here, we present a heavily pre-treat
Abstract The current online digital world, consisting of thousands of newspapers, blogs, social media, and cloud file sharing services, is providing easy and unlimited access to a large treasure of text contents.Making copies of these text contents is simple and virtually costless.As a result, producers and owners of text content are interested in
Background: Asthma may be considered as a non-communicable condition associated with higher bronchial responsiveness that may impair quality of life (QoL).Purpose: The research aim was to compare scores of depression, as well as general and foot health-related QoL, in patients who suffered from asthma with respect to healthy subjects.Methods: A tot
Animal and human pathogens that are transmitted by arthropods are a global concern, particularly those vectored by mosquitoes (e.g., Plasmodium spp.and dengue virus).Vector microbiota may hold the key to vector-borne pathogen control, as mounting evidence suggests that the contributions of the vector microbiota to vector physiology and pathogen lif
The double evolutional artificial bee colony algorithm (DEABC) is proposed for solving the single depot multiple traveling salesman problem (MTSP).The proposed DEABC algorithm, which takes advantage 12n/1200 wella of the strength of the upgraded operators, is characterized by its guidance in exploitation search and diversity in exploration search.T